DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE deuterium-labeled-amine 897 Purity (HPLC) >= 95%

897 Purity (HPLC) >= 95% Solubility DMSO

Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB Synonyms CAS Number Related CAS Molecular Formula C50H66N6O11 Molecular Weight 927

SiR-Maleimide is a far-red fluorescent probe containg maleimide function group for bioconjugation apploications

72 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

has enhanced potency in PIK3CA mutant models through a unique mechanism of action

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE deuterium-labeled-amine 897 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing