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Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Lenalidomide-CO-C2-acid Synonyms Lenalidomide-4'-CO-C2-acid

SKU 35510891040
4.0
EUR445.00 EUR490.00

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Description

Product Name Lenalidomide-CO-C2-acid Synonyms Lenalidomide-4'-CO-C2-acid CAS Number 1488107-60-3 Related CAS Molecular Formula C17H17N3O6 Molecular Weight 359

Product Name Thalidomide-5'-O-C6-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C19H24ClN3O5 Molecular Weight 409

Product Name Thalidomide-O-PEG2-OH Synonyms Thalidomide-4'-O-PEG2-OH CAS Number 2581818-54-2 Related CAS Molecular Formula C17H18N2O7 Molecular Weight 362

Product Name Thalidomide-5'-piperazine-C2-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C23H33Cl3N6O4 Molecular Weight 563

Product Name Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C64H87FN12O19 Molecular Weight 1347

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Lenalidomide-CO-C2-acid Synonyms Lenalidomide-4'-CO-C2-acidSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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